




Paroxetine
Paroxetine (non-hormonal) is a prescription option used to help manage moderate to severe vasomotor symptoms (VMS) associated with menopause, most commonly hot flashes and related nighttime symptoms. It’s an SSRI at a low, menopause-specific dose, and it is not estrogen.
Active ingredients
Paroxetine as paroxetine mesylate equivalent to 7.5 mg paroxetine base in the FDA-approved low-dose menopause product.
How to take
Once daily at bedtime, with or without food. Take it consistently at the same time each night. If you miss a dose: take the next dose at the usual time, don’t double.
Potential side effects
Side effects can happen, especially early on. Commonly reported categories include:
- nausea or GI upset
- sleep changes (sleepiness or insomnia)
- headache
- sweating
- weight changes
- sexual side effects





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