Microdosing Semaglutide Injection

Semaglutide is a GLP-1 receptor agonist that mimics the action of the natural GLP-1 hormone involved in appetite regulation and glucose signaling. By activating GLP-1 receptors, semaglutide may help you feel full sooner, stay satisfied longer, and reduce hunger cues—supporting lower overall calorie intake over time.

Microdosing is a low-dose strategy: a clinician keeps the dose below standard weight-loss dosing and fine-tunes it within that low range to balance comfort with progress, not up to a full dose.

Use semaglutide exactly as prescribed. It is typically administered as a subcutaneous injection once weekly, on the same day each week, with or without food.

Common injection sites include:

• Abdomen (stomach area)
• Thigh
• Upper arm

Rotate injection sites and avoid injecting into skin that is tender, bruised, red, or hard. Your clinician may adjust dosing over time to support tolerability and progress. If you miss a dose or have questions about timing, contact your care team.

Semaglutide may cause side effects. The most commonly reported include:

• Nausea
• Diarrhea
• Constipation
• Vomiting
• Stomach discomfort
• Decreased appetite
• Injection-site reactions

Side effects are often most noticeable when starting treatment or changing dose. A gradual, clinician-guided approach may help improve tolerability for some people. Seek medical attention for severe or persistent symptoms, signs of an allergic reaction, or severe abdominal pain.